KIFC1 and neoplasm: Inhibitors targeting KIFC1 have been developed, showing efficacy in blocking tumor growth and metastasis,[55, 56, 57, 58] as well as enhancing sensitivity to therapeutic agents.[22, 25, 26] In our study, the KIFC1 inhibitor AZ82 markedly inhibited the growth of STS both in vivo and in vitro, while concurrently promoting senescence.