FOLH1 and Familial prostate cancer: <h4>Purpose</h4>To evaluate the diagnostic performance of PSMA PET/CT, including [<sup>68</sup>Ga]Ga-PSMA-11 and [<sup>18</sup>F]DCFPyL, in comparison with the [<sup>99m</sup>Tc]Tc-MDP bone scan (BS) in identifying bone metastases among prostate cancer patients.<h4>Methods</h4>A search was performed in the PubMed and Embase databases to locate pertinent publications from inception to February 12, 2024.