Furthermore, the human orthologs of bgm, ACSBG1 and ACSBG2, are not currently associated with any human disease.43 We also studied the Acox1 gene in Drosophila downstream of ABCD1, and identified a unique ACOX1 variant that led to gain-of-function and lipid droplet accumulation (Mitchell syndrome, MIM 618960).28 However, again this study does not address the Drosophila Abcd1 ortholog. The gene discussed is ACSBG2; the disease is Mitchell syndrome.