RNA sequencing (RNA-Seq) and immunohistochemistry were performed on two different SCLC cohorts, and correlation analyses were performed for the <i>ASCL1</i>, <i>NEUROD1</i>, <i>POU2F3</i>, and <i>YAP1</i> genes and their corresponding proteins. The gene discussed is YAP1; the disease is small cell lung carcinoma.