This study examines the effect of inulin from dahlia tuber extract on blood glucose levels, serum insulin expression, pancreatic tissue insulin expression, homeostatic model assessment of insulin resistance (HOMA-IR), and the extent of insulitis in diabetic rats.<h4>Methods</h4>In this experimental study, 20 male Wistar rats were randomly allocated to five groups. This evidence concerns the gene INS and Insulin resistance.