Endometriosis is associated with decreased SOD activity in peritoneal fluid compared to that of fertile women (Liu et al., 2001; Szczepańska et al., 2003), and reduced SOD expression in the uterus is linked with aberrant endometrial function due to elevated oxidative stress (Chandra et al., 2009; Gupta et al., 2014). This evidence concerns the gene SOD1 and endometriosis.