HP and coronary artery disorder: In summary, our finding that HbA1c levels below 6.5% compared to 7.0-7.9% was associated with a reduced risk of CAD in the non-Hp2-2 phenotype group does not align with the finding from our previous ACCORD study, where no CAD benefit was observed with HbA1c below 7.0% in either Hp phenotype group.