The four infection-specific factors that scored positive are the STUB1 E3 ubiquitin ligase, which targets misfolded chaperone substrates toward proteasomal degradation, the HSPA2 chaperone, the SSRP component of the FACT complex regulating chromatin organization, and prohibitin 2 (PHB2), which acts, among others as a receptor for mitophagy. The gene discussed is PHB2; the disease is infection.