MKI67 and neuroendocrine carcinoma: The median Ki67 index of NEC-like G3NETs at initial and last examination was 10% (range 3 to 28) and 65% (range 50 to 85), respectively, with a median delta Ki67 value of 53 (range 37 to 68), which was significantly higher than that of G3NETs without NEC-like features (median 19, p < 0.0001, Table 1, Figs. 1 and 3a and b).