In tumor tissues from large specimens (especially from two tumor debulking samples), the histology showedmostly NEC-like features with high proliferation (Fig. 4a and b, ID3 in Table 2) and p53 overexpression (Fig. 4c, ID3 in Table 2) next to small foci of typical NET component without abnormal p53 expression. Here, TP53 is linked to neuroendocrine carcinoma.