Fig. 5B and C shows that co-infections with each rAAV individually or in combination and the helper virus yielded the expected patterns for the respective vector genomes, including high-molecular-weight concatemers. SalI treatment resulted in the disappearance of all bands representing ds dimers and higher-order multimers of the rAAV genomes. Instead, strong bands at 2 (Fig. 5B) and 3.8 kb (Fig. 5C), which are expected from cleavage of RCR products, appeared. Additional bands appeared at 2.4 (Fig. 5B) and 6 kb (Fig. 5C), which are consistent with RHR products. The gene discussed is ADRB1; the disease is coinfection.