DNA was isolated from the duodenal tissue using a commercial system and polymerase chain reaction (PCR) was performed on 7500 Fast PCR System.<h4>Results</h4>There were no associations between glucose tolerances, lipid levels and genotypes of <i>CPA1</i>, <i>GGT1</i>, <i>GPRC6A</i>, and <i>SPINK-1</i> in patients with IPMN. The gene discussed is SPINK1; the disease is pancreatic intraductal papillary-mucinous neoplasm.