To assess the relationship between Hp-enriched plasma proteins and AD biomarkers and cognitive measures, we conducted correlation analyses between Z-transformed protein abundance (Supplemental Table 22) and MoCA scores, as well as immunoassay values of CSF (Aβ1-42, tTau, pTau181, tTau/Aβ1-42) and plasma pTau181 (Supplemental Table 23). This evidence concerns the gene HP and Alzheimer disease.