IFNG and experimental autoimmune encephalomyelitis: Employing Il17aCreRosa26YFP fate reporter mice [90], we previously demonstrated that IL-17A-producing Th cells can produce IFN-γ alongside IL-17A, transitioning into IFN-γ-producing exTh17 cells that lose IL-17A expression in experimental autoimmune encephalomyelitis (EAE).