GATA2 and chronic obstructive pulmonary disease: We first enquired the expression level of GATA2 in macrophages from the lung tissues of COPD patients and smokers based on our previous single-cell RNA sequencing (scRNA-seq) dataset of human lung tissues from COPD patients and control donors [12] as well as that from smokers and non-smokers reported by Watanabe et al. [11].