HMOX1 and inflammatory bowel disease: The activation of TNF signaling has a potent effect on inducing cell death in intestinal epithelial cells, a process observed in the pathogenesis of various inflammatory diseases, particularly IBD.[30, 31] As anticipated, hAESCs administration significantly suppressed the expression of genes associated with intestinal epithelial cell inflammatory injury (Cxcl2, Hmox1, Reg3b, Reg3g, and Socs3), while enhancing the expression of a proliferation‐associated gene (Lgr5) compared to the control group (Figure S4b, Supporting Information).