For instance, FTO promotes synovial inflammation and joint damage in rheumatoid arthritis by stabilizing ADAMTS15 mRNA, while its inhibition reduces arthritis severity.[165] Similarly, KHSRP stabilizes FAK pathway mRNAs, facilitating pancreatic cancer progression, with targeting KHSRP suppressing tumor growth.[166] Therefore, the precise identification and characterization of these RNA modifications offer significant potential for the development of novel diagnostic tools and targeted therapies. This evidence concerns the gene FTO and familial pancreatic carcinoma.