VIRMA and colorectal carcinoma: This KIAA1429/SOX8 pathway underscores a potential therapeutic target for inhibiting CRC progression.[129] Similarly, USP13 upregulates and stabilizes METTL3 by removing K48‐linked ubiquitin chains, enhancing METTL3's ability to increase m6A levels and stabilize ATG5 mRNA, promoting autophagy and tumor progression.