This degradation disrupts the IGF2BP1‐mediated stabilization of PD‐L1 mRNA, pivotal for immune evasion.[148] In addition, LTN1 regulates cancer cell proliferation by ubiquitinating and destabilizing IGF2BP1, thereby inhibiting c‐Myc and IGF‐1R signaling pathways. This evidence concerns the gene IGF2BP1 and cancer.