For instance, FTO promotes synovial inflammation and joint damage in rheumatoid arthritis by stabilizing ADAMTS15 mRNA, while its inhibition reduces arthritis severity.[165] Similarly, KHSRP stabilizes FAK pathway mRNAs, facilitating pancreatic cancer progression, with targeting KHSRP suppressing tumor growth.[166] Therefore, the precise identification and characterization of these RNA modifications offer significant potential for the development of novel diagnostic tools and targeted therapies. The gene discussed is KHSRP; the disease is pancreatic neoplasm.