Thus, to confirm that the roles of TBC1D24 and SV2Bare unique to IgG-mediated infection, we generated corresponding clonal KO linesin K562 cells engineered to express DCSIGN (K562-DCSIGN), a cellular attachmentfactor that permits efficient DENV infection in the absence of IgG antibodies(74) (Table S5). Here, CD209 is linked to infection.