SLC1A2 and neoplasm: We next used a genetically engineered model (GEMM) harboring spontaneous MYCN-driven MBGRP3 tumors (GTML; Glt1-tTA/TRE-MYCN-Luc), to better reflect innate tumor development and pharmacology.40 Furthermore, the GTML orthotopic model provided a model where there was an intact BBB.