Following adjustments for variables such as age, smoking, drinking, pathological classification, surgery, recurrence, and metastasis, the risk of death in the Ki67 (70-100%) laryngeal cancer group was determined to be 2.0504 times (1.2997, 3.2345) higher than that in the Ki67 (0-35%) index level group (P=0.0020). The gene discussed is MKI67; the disease is laryngeal carcinoma.