Recognising that bleeding questionnaires could be of limited benefit in a very young patient with a short personal medical history, it is unfortunate that the value of standard laboratory tests such as the activated partial thromboplastin time (aPTT) or prothrombin time (PT) to screen for inherited or acquired bleeding disorders may be limited or of no value, especially in selected patients with mild bleeding disorders (Table 1, Table 2).21 This evidence concerns the gene F2 and hemorrhagic disease.