Proper regulation of the IGF signaling pathway is crucial for maintaining cellular growth, function, and metabolic balance, and its dysregulation is linked to diseases such as cancer, diabetes, and growth disorders (Mancarella et al., 2021; Forbes et al., 2020; Altieri et al., 2019; Okuyama et al., 2021; Stefani et al., 2021; Jiating et al., 2019; Yang et al., 2020; Chaumont-Dubel et al., 2020). The gene discussed is IGF1; the disease is cancer.