Additionally, the high MSI scores in Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (DLBC), HNSC, Mesothelioma (MESO), KIRP, LUSC, Thyroid carcinoma (THCA), Rectum adenocarcinoma (READ), Skin Cutaneous Melanoma (SKCM), and STAD are positively correlated with R3HDM1 expression. The gene discussed is R3HDM1; the disease is rectum adenocarcinoma.