ERBB2 and neoplasm: Ivanova et al. (2020) report the establishment of patient xenograft-derived organotypic tumouroids (PXDOT) from patient-derived exon 19 and exon 20 HER2-mutant NSCLC xenografts (PDX). These PDX tumours were processed and cultured in ULA plates for spheroid formation, followed by transferring spheroids to microfluidic devices and exposed to different drugs and drug combinations (Jenkins et al., 2018).