CXCL10 and neoplasm: Newly strategies including plasmid-borne CXCL9 (12), intratumor injection of CXCL9 (13), recombinant CXCL10 protein with adoptive cell therapy (ACT) (14), intra-tumor injection of CXCL10 (15), retroviral transduction tumor cells with CXCL10 (16, 17) were effective in increasing T cell infiltration and reducing tumor growth in animal models (18).