Recent epigenomic assessments have unearthed specific DNA methylation aberrations in genes pivotal to PD, such as SNCA (188), Transmembrane and coiled-coil domain family 2 (TMCC2) (189), Solve Carrier Family 17 Member 11 (SLC7A11) (190), HOX transcript antisense RNA (HOTAIR) (191), SLC17A6 (VGLUT2), PARK7 (DJ-1), PTPRN2 (IA-2β), and NR4A2 (NURR1) (192) (Table 3). Here, SNCA is linked to Parkinson disease.