The link between VDAC1 and SARS-CoV-2 was demonstrated, by the overexpression of VDAC1 in a population of T cells, suppression of mtDNA release, cGAS-STING pathway activation and improved survival in the T cells of COVID-19 patients when treated with the VDAC1-interacting compound VBIT-4 [33]. This evidence concerns the gene STING1 and COVID-19.