For LPS‐induced inflammation modulation, two schemes can be adopted: 1) using probiotics or antibiotics to inhibit intestinal bacterial translocation to inhibit LPS‐mediated TLR4 activation, and 2) directly inhibiting the activation of LPS‐mediated TLR4.[33] Studies have shown that probiotics and antibiotics can reduce liver injury caused by TLR4 activation‐induced hepatitis. This evidence concerns the gene TLR4 and hepatitis A virus infection.