KEAP1 and multinodular goiter: Genetic analysis of 39 patients with familial multinodular goiter (see Fig. 1) identified 4 newly heterozygous variants in germline KEAP1 (c.256C > T, p.Q86*; c.407T > C, p.L136P; c.1231_1232insG, p.V411fs; and c.1243C > T, p.R415C), in addition to the previously reported variant (c.1448G > A, p.R483H) (8).