YTHDF3 and breast carcinoma: We introduced point mutations W438A and W492A in the YTH domain of FLAG-tagged YTHDF3 (YTHDF3-OE-mut) and transfected breast cancer cells with constructs expressing either wild-type YTHDF3 (YTHDF3-OE-wt) or mutant YTHDF3 (YTHDF3-OE-mut) (Figure 3C).