CXCR4 and neoplasm: Inhibition of tumor growth, quantified by bioluminescence imaging (Fig. 1c and dupper panels), revealed that although both viruses significantly inhibited tumor growth compared to untreated tumor-bearing mice, treatment with OV-CXCR4-A exhibited higher efficacy compared to the control counterpart (Fig. 1c, lower panel; p < 0.01).