HIF1A and neoplasm: Consistent with the ST analysis, the highest number of Arg1-expressing tumor-infiltrating myeloid cells was detected after the ACT monotherapy compared to other treatments (Fig. 5eupper panel; and f), whereas the expression of Hif1a dominated in myeloid cells after the OV-Fc/ACT combination treatment, with some cells expressing both antigens (Fig. 5elower panel; and g and h, respectively).