TLE4 and Tuberculosis, Bovine: Many potential biomarkers identified in the present pan-genome analysis have previously been reported as potential antigens to improve the serological diagnosis of human and/or bovine tuberculosis: Rv3872 (PE35), Rv3874 (CFP10), Rv3875 (ESAT6), Rv3876 (EspI) in RD1 (93–96), Rv1573, Rv1577c in RD3 (97), or Rv1508c, Rv1509, Rv1514c, Rv1516c in RD4 (93, 97).