Performing a similar analysis for colonic macrophages and monocytes in paired CRC metastasis, 1,330 macrophage and monocyte cells were clustered (Figure S10E).32 Resident macrophage markers VSIG4 and CSF1R were found to be highly co-expressed in the left region of the UMAP (Figure S10B). The gene discussed is VSIG4; the disease is colorectal carcinoma.