Interestingly, a significant correlation was found between the expression of TGF-β, IL-6, TLR-2 and TLR-4 by the primary CRC tumor and FN1 expression in the metastatic intrahepatic tumor (Figure 6F–I) but no correlation to the local primary CRC tumor (Figure 6J–M). This evidence concerns the gene TLR4 and neoplasm.