PTX3 and obesity due to melanocortin 4 receptor deficiency: Circulating PTX3 concentrations are negatively correlated with various obesity indices, including BMI, waist and hip circumference, and visceral fat mass (Zempo-Miyaki et al., 2019; Osorio-Conles et al., 2011; Chu et al., 2012; Miyaki et al., 2012; Slusher, Huang & Acevedo, 2017).