METTL14 and hepatocellular carcinoma: In hepatocellular carcinoma(HCC), intestinal bacterial lipopolysaccharide regulates the expression of PD-L1 on the surface of cancer cells by upregulating METTL14 and METTL14-mediated m6A modification of MIR155HG, modulating the miR-223/STAT1 axis (135).