IL6 and acute kidney injury: In a murine model of LPS-induced acute kidney injury, AT-RvD1 alleviated the inflammatory response and protected kidney function by reducing the expression of ICAM-1 and vascular cell adhesion protein 1 (VCAM-1), inhibiting IL-6 and IL-6-related inflammatory pathways (STAT3 and ERK phosphorylation), and reducing the phosphorylation and activation of NF-κB (38).