The aggregated findings illustrated a positive correlation between an elevated density of FOXP3+TILs and shortened OS in patients diagnosed with NSCLC (HR=1.35, 95%CI: 0.87-2.11, P>0.05, Figure 4A), with significant aheterogeneity (I2 = 88.7%, P<0.001). This evidence concerns the gene FOXP3 and non-small cell lung carcinoma.