In addition, UCHL1‐specific inhibitor, LDN‐57444, significantly reduced NE markers expression, as well as delayed tumor growth of multiple NE carcinoma xenografts, including NEPC (NCI‐H660), SCLC (NCI‐H82), and neuroblastoma (IMR‐32) cell line, and NEPC and SCLC PDX models in vivo.161. The gene discussed is UCHL1; the disease is small cell lung carcinoma.