Numerous studies have demonstrated the efficacy of radiomics in accurately predicting the Ki-67 index across various tumor types, such as lung cancer (61), breast cancer (62),and glioma (63).Recent research has also validated the potential of radiomics in prognosticating the Ki-67 index in pituitary tumor tissues, underscoring its growing relevance in the field of oncological biomarker identification and prognostic assessment. This evidence concerns the gene MKI67 and central nervous system cancer.