Studies have shown (13) that GLP-1R is expressed in normal pancreatic islet, acinar and duct cells, and Waser (83) reported that GLP-1R is highly expressed in normal pancreatic secretory cells, expressed at low level in pancreatic acinar cells, not expressed in pancreatic duct cells, and expressed at low or no levels in human pancreatic cancer tissues. Here, GLP1R is linked to familial pancreatic carcinoma.