Laboratory analysis revealed an hypergonadotropic hypogonadism with a luteinizing hormone (LH) of 11.04 mIU/mL (reference range (RR) 1.3-12.9), a follicle-stimulating hormone (FSH) of 30.81 mIU/mL (RR 0.9-15.0), a total testosterone (TT) of 1.56 ng/mL (RR 2.7-10.7) and a free testosterone (FT) of 7.6 pg/mL (RR 8.8 - 27.0). This evidence concerns the gene PLOD1 and Hypergonadotropic hypogonadism.