For this purpose, we analyzed mutations in CDC25B and hub genes (CCNB1, BUB1B, BIRC5, KIF23, DLGAP5, CDK1, KIF11, NCAPG, KIF2C, and CDCA8) in HCC samples at the cBioPortal database (Figure 6(a)). The gene discussed is CCNB1; the disease is hepatocellular carcinoma.