MTOR and melanoma: Resveratrol (trans-3,5,4′-trihydroxystilbene), which is a stilbenoid phenolic compound found in berries, grapes, and peanuts, induces autophagy by modulating Rictor (a component of mammalian target of rapamycin complex [mTORC]2) in squamous carcinoma cells57 and activates autophagy in B16 melanoma cells by accumulating ceramide and suppressing the Akt/mTOR pathway.58