Individuals with iGHD were shown to cope better with the SARS-CoV-2 infection than controls; this might be related to altered secretion of adipokines and cytokines like interleukin 6 (IL-6), TNF-α and interferon, which altogether may limit immune-related tissue destruction due to the infection with SARS-CoV-2 [129]. Here, IL6 is linked to isolated congenital growth hormone deficiency.