Biomarkers of oxidative damage to biomacromolecules (8-iso-PGF2α, AOPP, MDA) were significantly elevated, while vitamins & carotenoids (β-carotene, lycopene, total carotenoids, vitamin A, vitamin C, β-Cryptoxanthin), proteins (albumin, Selenoprotein P, transferrin, R–SH), and other markers (TAC, TBIL, selenium) were significantly reduced in inactive disease compared to healthy individuals. Here, ALB is linked to Lethargy.