PRDX6 has been linked to depressive (Gu et al., 2022) and anxiety-like (Pairojana et al., 2022) behavior in mice as well as to paroxetine (McHugh et al., 2010), escitalopram, and sertraline (Bisgaard et al., 2012) administration in rats. The gene discussed is PRDX6; the disease is Anxiety.