BDNF and neurodegenerative disease: For example, brain‐derived neurotrophic factor (BDNF), a crucial molecule with multiple implications in memory, ageing and neurodegenerative diseases (Miranda et al., 2019), is released from presynaptic dense‐core vesicles in an activity‐dependent manner (Dieni et al., 2012; Kohara et al., 2001).