RAF1 and acute kidney injury: In our study, Stattic treatment in L-AKI mouse alters the noncanonical pathways related to cell proliferation and survival gene profiles, including Raf1 (RAF proto-oncogene serine/threonine-protein kinase; MAPK signaling pathway) and mTOR (Mechanistic target of rapamycin kinase; PI3K-AKT signaling pathway) [2, 42].