In another study, live T. vaginalis isolate T016 and its excretory–secretory product induced apoptosis of human cervical cancer cells (SiHa cells), and vaginal epithelial cells (MS74 cells) in a parasite-dose-dependent manner through the induction of mitochondria-dependent apoptosis via the dissociation of Bcl-xL/Bim and Mcl-1/Bim complexes [306]. This evidence concerns the gene BCL2L11 and cervical carcinoma.