Simultaneously radiation induced a higher number of MRE11 foci, which also indicates a problem with repair [40] An impairment of nucleoshuttling of the ATM protein to the nucleus and a delayed phosphorylation of ATM has been described in several diseases with neurological defects and cancer proneness [41] e.g. Xeroderma Pigmentosum [42], Huntington’s disease [43] and Neurofibromatosis type 1 [44]. This evidence concerns the gene ATM and juvenile Huntington disease.