PTPN6 and rectum adenocarcinoma: Except for the differential expression between the tumor and adjacent normal tissues for ptpn6 in TIMER2 database mentioned above, ptpn6 expression was also significantly higher in acute myeloid leukemia (LAML), brain lower grade glioma (LGG), ovarian serous cystadenocarcinoma (OV), rectum adenocarcinoma (READ), testicular germ cell tumors (TGCT), and uterine carcinosarcoma (UCS) than that in paired normal tissues (Fig. 1B).