PTPN6 and mesothelioma: In addition, we also investigated the correlation between CAFs and ptpn6 expression, and found that ptpn6 expression was positively correlated with CAFs in COAD, HNSC-HPV-, LGG and THCA, while negatively correlated with BRCA-LumA/LumB, mesothelioma (MESO) and THYM (Figure S4).